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Nevertheless, sulphasalazine has been demonstrated to be an effective treatment in cancer models, by inhibiting xCT to activate ferroptosis 232,233 and restore sensitivity to chemotherapy

In co-exposure, a potentiation effect was observed, with DPDS + TMZ significantly reducing GBM cell density compared to the DMSO, TMZ, DPDS 10 M, and DPDS 20 M groups, indicating a pro-cytotoxic interaction between DPDS and TMZ in GBM (Fig

& Lederkremer, G

Although appetite was not studied a modulation of microbiota affected anxiety in larval zebrafish larvae, and Lactobacillus plantarum (a probiotic) reduced anxiety-related behavior in conventionally-raised zebrafish larvae ( However, carp fed a diet supplemented with fructo-oligosaccharide (FOS) display increased levels of heterotrophic aerobic bacteria and LAB, but no changes in feeding rates compared to fish fed a control diet (Hoseinifar et al., 2014)
