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These treatment results suggest that the old age increases in Rab7-labeled late endosome and Arl8b-labeled lysosomes are not protective but suffer from insufficient energy to complete the processes of vesicular autophagy via lysosomal degradation

In contrast to the immunopathology observed after immunization with MVA-S, other studies of SARS-CoV have suggested a protective effect of vaccine-induced antibodies

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The principal mCpG binding interface composed of hydrophilic and hydrophobic residues involves two types of interaction with mCpG steps: the polar atoms in MBD form hydrogen bonds with the polar atoms in the DNA, while the non-polar atoms in MBD form a hydrophobic patch around the methyl groups