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Among the secreted factors, extracellular vesicles (EVs) and mainly exosomes have emerged as novel communication vehicles that have been detected in the TME and are increasingly understood as key players in tumor growth and spread [133,134]
10.1371/journal.pone.0002719 PLoS One 46 GeemD.Medina-ContrerasO.McBrideM.NewberryR
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