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They also clarified in another clinical study that supplements with glycine (1.33 mmol/kg/day) and N-acetylcysteine (0.81 mmol/kg/day) for 24 weeks corrected erythrocyte-GSH deficiency and alleviated oxidative stress and mitochondrial dysfunction in elderly individuals [110]
This approach eliminates M.tb through mechanisms that bypass the pathways commonly targeted by conventional anti-TB drugs, thereby reducing the risk of developing antibiotic resistance [5, 7]

Glutathione Depletion Is Linked with Th2 Polarization in Mice with a Retrovirus-Induced Immunodeficiency Syndrome, Murine AIDS: Role of Proglutathione Molecules as Immunotherapeutics
Reductive metabolism of nitrofurantoin by rat lung and liver in vitro
