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Description
doi: 10.1016/s0891-5849(02)00956-5
Within hepatocytes lactate binds to soluble adenylate cyclase (sAC) thereby activating a signaling cascade resulting in increased expression of the HAMP gene that encodes hepcidin
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Moreover, it also increases the production of interleukin-1 (IL-1), which facilitates T helper 17 (TH17) responses
