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Based on its powerful anti-inflammatory and neuroprotective activities, minocycline, a tetracycline antibiotic that can cross the BBB, is a candidate for the treatment of depression and anxiety
The Eastern Mediterranean Region (EMR) covers an area of 22 countries between Morocco and Pakistan, and Afghanistan with a population of approximately 725 million people in 2020
doi: 10.1186/s13046-020-1528-x 120 WangLYangQPengSLiuX
Serotonin also plays a role in the CNS and controls many stress mechanisms such as the HPA axis through stimulation of corticotropin-releasing hormone (CRH) (432)
