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Developing mitochondrial base editors with diverse context compatibility and high fidelity via saturated spacer library
In these models, we take into account the reaction geometry of common thiol-disulfide exchange reactions and distinguish hypothetical protein areas that might either interact with the disulfide substrate (a scaffold site) or the reducing agent (an activator site) (Fig
Oncotarget 9 , 3537835393 (2018)
Stierum et al
