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This interaction helps explain both its vascular effects and its apparent benefits for various organ systems beyond musculoskeletal tissues

Therefore, scientists have focused on enhancing the selectivity of F16 and its derivatives for tumor cells, and future research will likely uncover new drugs that can specifically target tumor cell mitochondria and reduce toxic effects on normal cells

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To generate transgenic lines, a 2-kb promoter region of PIF4 was fused with PIF4 CDS (wild-type and mutant versions) and cloned into pJHA212H between EcoRI and BamHI along with a C-terminal (PT) 4 P linker , mGFPmut2 , and a His-tag