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Data availability The datasets generated and/or analysed during the current study are available from the corresponding author on reasonable request

Adding tamoxifen (10-20mg daily) blocks estrogen receptors in breast tissue without affecting estrogen elsewhere

Animal studies showed dose-dependent GH release comparable to GHRP-6 but with a cleaner side effect profile

We used specific Taqman probes for IGF-I (Mm00439560_m1), IGFBP-4 (Mm00494922_m1), IGFBP-5 (Mm00516037_m1), GHR, (Mm004390093_m1), IGF-IR(Mm00802831_m1), and gene expression related to osteoblastic and osteoclastic activity such as, CTR (Mm00432271_m1), SOST (Mm00470479_m1), PTHR1 (Mm00441046_m1), Runx2 (Mm00501584_m1), RANKL (Mm 00441908_m1), and OPG (Mm00435452_m1), supplied by Applied Byosistems