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Individual factors like age, weight, and baseline IGF-1 guide dose adjustments
Extensive functional diversification of the Populus glutathione S -transferase supergene family
This finding indicates the main challenges related to -PL production, i.e., low yield and low production, respectively arising due to co-products potentially generated by these biosynthetic gene clusters during fermentation (Figure 3), and unknown rate-limiting steps in the -PL biosynthetic pathway (Yamanaka et al., 2020)
