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Interestingly, L585 could only be replaced with an amino acid having similar physiochemical properties, including isoleucine, methionine, and valine, without negatively affecting FcRn binding 64

66 WangY.ShanZ.ZhangL.FanS.ZhouY.HuL.et al (2022)

Key Research Insights DSIP was discovered as a sleep peptide in 1974, but research now shows it affects multiple body systems beyond just sleep patterns
