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Targeting AKR1B1 inhibits glutathione de novo synthesis to overcome acquired resistance to EGFR-targeted therapy in lung cancer

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[DOI] [PMC free article] [PubMed] [Google Scholar] 109.Su D, Novoselov SV, Sun QA, Moustafa ME, Zhou Y, Oko R, Hatfield DL, Gladyshev VN

Humans generate billions, if not trillions of different antibodies over a lifetime, each capable of binding to a distinct epitope (the docking station) of an antigen
