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Whitney ER, Kemper TL, Bauman ML, Rosene DL, Blatt GJ

To survive inside phagocytic cells and avoid degradation, can live within the phagolysosome by employing two mechanisms: capsule enlargement and pH modification of the phagolysosome
Due to low cost, easy availability and high efficacy, MTX is the most important and commonly used DMARD in developing and low income countries
