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doi:10.22074/cellj.2016.4872 [10] Sandhir R, Sood A, Mehrotra A, Kamboj SS

In MASLD, reduced SIRT1 activity leads to hyperacetylation and stabilization of PLIN2 and PLIN3, effectively locking lipid droplets and impairing lipophagic clearance, exacerbating triglyceride accumulation

Likewise, CD4 + T cells, other inflammatory cells like, basophils, lymphocytes, eosinophils neutrophils, monocytes and mast cells are also taking parts in this process, with eosinophil recruitment being the main feature and chemokines perform an important role in the activation and migration of inflammatory cells into the respiratory airway