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Metformin showed efficacy in the treatment of antipsychotic-induced weight gain, dyslipidemia, and metabolic abnormalities in schizophrenia [416]
Defensins and cathelicidins (e.g., LL-37), two mammalian AMPs, are particularly interesting templates for drug design due to their effectiveness against microbial cell membranes
Unfortunately, the outcome of the trial was Sativex did not produce a statistically significant reduction in the severity of spasticity in this patient population
