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These cells, also referred to as double-negative (DN), late, or tissue-like memory B cells, are enriched in both infectious and autoimmune diseases [139, 140]

we can presume that deletions causing frameshifts would be lethal

D.BachaH.The role of oxidative stress in zearalenone-mediated toxicity in Hep G2 cells: Oxidative DNA damage, gluthatione depletion and stress proteins induction2007294 EOF302 EOF 127

This unique property means both local and systemic administration can support healing, though local injection near the injury typically produces faster results
