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These previous and current studies point towards the requirement of proactive research in the immunopathology caused by COVID-19

Major protein deacetylases in the cell can be classified as histone deacetylases (HDACs) or sirtuins (SIRTs)

Annexin V + /PI cells were identified as early apoptotic, and Annexin V + /PI + cells as late apoptotic or necrotic

To overcome these burdens, modern technology attempted to replace conventional treatments by designing smart hybrid nanosystems that can deliver drugs to localized sites to prevent infection by overcoming barriers imposed by biofilms and regulating complex wound microenvironment, thus promoting tissue regeneration in the wounded site