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Description
The product of this gene (i.e., GGT-rel) was shown to cleave the -glutamyl bond of LTC 4 (a glutathione S -conjugate) but not the -glutamyl substrates routinely used to assay GGT activity
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Methods: This article is a Systematic Review that synthesizes recent multi-omics and clinical evidence on mechanisms (hormonal, immune-inflammatory, oxidative stress/ferroptosis, genetic/epigenetic, microbiome/metabolic) and appraises therapeutic strategies spanning surgery, hormonal suppression, assisted reproductive technologies (ART), and emerging adjuncts
nitric-oxide signaling
