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Development of insulin resistance and obesity in mice overexpressing cellular glutathione peroxidase
Hereditary non-polyposis colorectal cancer: The rise and fall of a confusing term
Age-related reduction of mitochondrial function is accompanied by a decline in the mitochondrial capacity for ATP production by oxidative phosphorylation [62], a reduction in the NAD + pool [63] by consuming processes (PARP, CD38, and SIRT1) [64], and further an increase in ROS generation by an inefficient electron transport chain (ETC) [26]
Additionally, following challenge E4 mice preserved a higher proportion of acylcarnitine in the brain relative to the periphery compared to E2 and E3 mice
