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This process is facilitated by the protonation of amine groups grafted onto the polymer surface within endosomes (pH 56) and lysosomes (pH 45), which possess strong proton-buffering capacity and induce rapid osmotic swelling, thereby promoting cargo release

Methods combining hot water extraction with ultrafiltration have demonstrated the capability to achieve EGT purity of up to 99.0% [36]

IV therapy bags are designed to let gravity (as opposed to a syringe or other forced technique) to carry fluid into the veins over time

NCCN Clinical Practice Guidelines in Oncology: Management of Immunotherapy-Related Toxicities