Gluathione: A Super Antioxidant
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Description
Intellia Therapeutics NTLA2001 targets transthyretin (TTR) for treating transthyretin amyloidosis (ATTR)
Management is focused on treatment of the underlying condition
The tissue samples were homogenized in PBS (pH 7.4) containing 0.1 mmol/L butylated hydroxytoluene (BHT) (TissueRuptor, Qiagen, United States) and sonicated for 30 s in an ice bath (Ultrasonic bath, Branson, United States)
Taken together, these results demonstrate that the ability of MBP to promote the solubility of its fusion partners in vitro does not always result in their proper folding, as has also been observed in vivo [7]
