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They are responsible for single- and double-strand breaks of the DNA, with the latter being considered as the predominant cause of cell death after ionizing radiation exposure
Design and synthesis of novel 3-(benzo[d]oxazol-2-yl)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine derivatives as selective G-protein-coupled receptor kinase-2 and -5 inhibitors
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