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Description
The FOXO4 transcription factor, which usually helps cells repair themselves or undergo apoptosis when damaged, gets sequestered by p53 in senescent cells
Previously in an inactive form that had to be converted in the liver
Gut Barrier Damage and Malabsorption Caused by Alcohol Alcohol disrupts the gut microbiome and damages the intestinal barrier, contributing to dysbiosis, increased permeability, and impaired nutrient absorption
doi: 10.2215/CJN.09990819
