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Description
La L-Carnitina se encuentra naturalmente en varios alimentos, siendo las carnes rojas y los productos lcteos las fuentes ms ricas

Pharmacokinetic modelling suggested a 3compartmental distribution with mean residence times of 1 h (central compartment), 12 h (fast equilibrating compartment such as liver and kidney) and 191 h (slow equilibrating compartment such as skeletal and cardiac muscle), suggesting that transfer of Lcarnitine from plasma to the main carnitine pool is a slow process taking days to weeks

This fact hinders consumer trust and affects product positioning, particularly in markets with stringent health claim regulations

Understanding how TMAO affects various immune cells, including macrophages, DCs, T lymphocytes, B lymphocytes, and natural killer (NK) cells, is of great significance in further unraveling the complex mechanisms of immunometabolism and potentially developing new therapeutic strategies
