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Bonferronis correction was applied to analyses correlating BAL fluid or intracellular GSH, GSSG, and GSH:GSSG to up to 5 gene expression variables or clinical parameters to adjust for multiple comparisons
Mechanistically, DMF regulates the expression of factors involved in the de novo cysteine synthesis (CBS), cystine uptake (SLC7A11), and GSH generation (GCLC, GCLM) through NRF2-dependent and independent pathways
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