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[2] Pharmacokinetic studies demonstrate rapid systemic distribution with peak plasma levels occurring within 30-60 minutes of intramuscular injection, followed by extensive hepatic storage and enterohepatic recycling

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[DOI] [PMC free article] [PubMed] [Google Scholar] 24.Aksoy S, Szumlanski CL, Weinshilboum RM

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The frequency of injections depends on individual needs and medical advice, but many people receive injections once a week if they are deficient

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