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Hibberd TJ, Feng J, Luo J, Yang P, Samineni VK, Gereau RW, Kelley N, Spencer NJ (2018) Optogenetic induction of colonic motility in mice

excessive use may cause imbalances or mild adverse reactions

It is important to note that neurological damage can occur before haematological changes become apparent, and symptom severity does not always correlate with the degree of biochemical deficiency
