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The skin is the largest organ in the human body, comprising up to 16 percent of total body weight (83)

Effect of intra-ovarian injection of mesenchymal stem cells or its conditioned media on repeated OPU-IVEP outcomes in Jersey heifers and its relationship with follicular fluid inflammatory markers

Gaanin, J

But there is a grey/intermediary zone that exists (148-500 pmol/L ish), where patients may be deficient on a cellular level (in energy cycle and methylation) and wildly symptomatic including overt bilateral neurological symptoms, cognitive symptoms, severe fatigue (usually in the absence of anaemia) etc
