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J.SellS.et al (2019)
By inhibiting HDAC6, Vorinostat reduces IL-10 levels, which decreases M2 macrophage polarization and consequently limits tumor growth

Under normal physiological conditions, nuclear factor erythroid 2-related factor 2 (Nrf2) remains sequestered in the cytoplasm through its association with Kelch-like ECH-associated protein 1 (Keap1)
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