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Dosage may be reduced to 0.5 mL weekly in patients experiencing gastrointestinal intolerance or increased to a maximum of 2 mL twice weekly for short-term metabolic intensification when supervised by a qualified clinician

10 , eaat3392 (2018)

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Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors
