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Considering significant heterogeneity between studies [23, 26] when we compared difference values about 6-minute walk, meta-analysis with random-effect model revealed that there were no significant differences in improvement of exercise tolerance between the two treatments (WMD: 45.41 m, 95% CI: 14.46 to 105.29, P = 0.14, Figure 3(b))

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The concentration of above carnitines was negatively correlated with the score of the Hamilton scale (33)