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In humans, once-weekly subcutaneous dual GLP-1R/GIPR agonist LY3298176 administration obtained greater weight loss and glucose control than dulaglutide, with an acceptable tolerability profile [166]

Dose-response, efficacy, and safety of oral semaglutide monotherapy in Japanese patients with type 2 diabetes (PIONEER 9): a 52-week, phase 2/3a, randomised, controlled trial

Mann JFE, Hansen T, Idorn T et al (2020) Effects of once-weekly subcutaneous semaglutide on kidney function and safety in patients with type 2 diabetes: a post-hoc analysis of the SUSTAIN 17 randomised controlled trials

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