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Smoking is associated with altered endothelial-derived fibrinolytic and antithrombotic factors: an in vitro demonstration

The resulting 7-methylxanthine is methy- lated by 7-methylxanthine methyltransferase (MXMT or theobromine synthase) to produce 3,7-dimethylxanthine (theobromine) (step 3), which is further methylated by 3,7-dimethyl- xanthine methyltransferase (DXMT or caffeine synthase) to give caffeine (1,3,7-trimethylxan- thine) (step 4)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 374.Abate BB, et al
