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Further research evidence on NRT safety is needed, ideally from placebo-controlled RCTs that achieve higher adherence rates, monitor infants outcomes into childhood, and investigate higher doses of NRT than those tested in the included studies 1

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Young smokers without respiratory symptoms experienced the same longitudinal changes in FEV 1 as non-smokers [50]

In addition, the study cohort consisted of middle-aged European participants, so our findings may not be generalized to other age groups and ethnic populations