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This was confirmed by testing for cotinine (a nicotine breakdown product) in urine or saliva

Renal biopsy specimens taken from cigarette smokers showed a range of long-term changes with varying degrees of glomerulosclerosis, ischemic glomeruli, interstitial fibrosis and tubular atrophy, and arteriolar hyalinosis [16], This broad spectrum of histologic findings combined with initial renal hyperfiltration suggested that cigarette smoking induced renal damage was primarily the result of alterations of renal hemodynamics and its sequelae on glomerular and tubular function /structure [17,18,19]

In some cases, you may have a smokers cough for years after you quit

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