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A systemic review with meta-analysis confirmed an association between the use of ST and risk of fatal myocardial infarction (MI) and stroke.[15] Combining information from both developing and developed countries, it is observed that odds of having acute MI was more among users of ST compared to nontobacco users.[17,18,19,20] Due to the high background rates of CVD, even a small increase in risk clearly could represent a large public health impact in countries that have a high prevalence of ST use.[1,2,7,21] Multiple studies have reported that all forms of tobacco use is highly prevalent in youth and adult and in both men and women in India