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Compliant with medications and office visits, but If I dont have a cigarette, I cant think, I cant read, I become disoriented If I cant smoke, I dont care if I live or die. SFGH Cardiac Clinic - May 1, 1996 DIAGNOSINGTOBACCOADDICTION:DSM-V(Tobacco UseDisorder) A problematic pattern of tobacco use leading to clinically significant impairment or distress, as manifested by at least two of the following, occurring within a 12-month period: Tobacco is often taken in larger amounts or over a longer period than was intended

Details on how these statistically significant estimates were applied to each WHO sub-region can be found in web Additional file 1: Appendix 4