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Anti-seizure medication, for example, can decrease the number of instances if a seizure disorder is the problem

Furthermore, clinical trials have shown that standard NRT doses are inadequate for rapid metabolizers of nicotine (i.e., those who inactivate nicotine to cotinine and then to 3-hydroxycotinine [3-HC] more quickly than others due to genetic variation affecting the activity of the hepatic enzyme CYP2A6) [20, 25]

Gao, D., Li, X

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