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Patients who took at least two pills a week for 6 months or more had a median age of symptom onset of 64 years
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The subjects with diabetes, hypertension, obesity, renal diseases lipid metabolism disorders and coronary diseases were excluded
While its difficult to pinpoint a definitive explanation given some data gaps (limited historic financials in the S-1), I think one plausible answer is that stabilizing the core became a higher priority throughout the 2010s
