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More importantly, these investments enable business capabilities and outcomes that allow them to thrive in even the harshest economic conditions. The Gartner report states that: "In our 16th edition of the Supply Chain Top 25, we have an impressive group of leaders with new lessons to share, including a diverse set of six new entrants. It further mentions that, with substantial portions of the economy closed due the COVID-19 pandemic, we are seeing unemployment and negative economic growth rates on a scale not seen since the early 20th century in some cases. Further, leaders need an agile, or adaptive, strategy that allows the supply chain organisation to sense and respond to changes in the business context as they happen. Regarding the Supply Chain Top 25 Methodology, Gartner states, the ranking comprises two main components business performance and opinion

The important secondary metabolites found in some of the parts of tobacco are summarized in Table 1

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