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Contact with NNA led to DNA damage, including double-strand breaks, the most deleterious genotoxic outcome. To better understand dermal exposures, Consortium researchers at UC Riverside and UC San Francisco evaluated how NNK and nicotine penetrate through the skin of mice

Restricted cubic spline analyses were applied to characterize the dose-response relationship and explore the potential non-linear association between the average daily consumption of each type of tobacco product with hypertension risk

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As you might imagine, these chemical reactions require energy to come from somewhere