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Once they smell, they will crawl as fast as they can to find the source

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Third, individuals who successfully transition from cigarettes to e-cigarettes may differ from the general non-smoking population in unmeasured ways, including greater health awareness, higher engagement with healthcare services, and more favourable lifestyle behaviours not fully captured by the available covariates

When smokers respond to this craving by increasing nicotine intake, a parallel increase (upregulation) in nicotine receptors occurs in the brain, causing observable physiologic changes