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It differs from moist snuff or chewing tobacco in that it is made from steam-cured tobacco leaves, rather than fire-cured ones, and its health effects are markedly different, with epidemiological studies showing lower rates of cancer and other tobacco-related health problems than cigarettes, American "chewing tobacco", Indian gutka or African-type tobacco products

Department of Public Health (DPH)

For example, the joint effect of two dichotomous exposures E 1 and E 2 (coded 1 = exposure present, 0 = exposure absent) on the rate difference is the sum of their singular effects: Hence the term additive model