Mixture No. 79
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In studies of duloxetine in smoking and nonsmoking psychiatric patients (not directly related to pain relief), serum levels of the drug were lower in smokers than in nonsmokers, suggesting that tobacco smoke components induce drug-metabolizing enzymes (e.g., cytochrome P450 1A2) [108, 109]
Nelson LS, Goldfrank LR
[PubMed] [Google Scholar] Gonzales 2002a Gonzales D, Bjornson W, Durcan MJ, White JD, Johnston JA, Buist AS, et al
