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Maher Karam-Hage, a tobacco treatment expert and addiction specialist at the University of Texas MD Anderson Center, explained in a center article

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In the centipede market legend, there is a case where a giant centipede about 200 meters long fights with a toad the size of a dog and both die
A naturalistic study in people with schizophrenia found no significant difference in severity of symptoms between smokers and those who had quit smoking (Krishnadas Reference Krishnadas, Jauhar and Telfer2012)