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Under different concentrations of e-cigarette aerosol exposure (10, 20, 30, 40, and 60 mg/mL), a significant increase in the DA signal curve in the NAc of mice could be observed (Figure 1E), with most nicotine or nicotine salts reaching a peak signal and gradually falling back after approximately 40 min of exposure, after calculating the highest point peak and counting the intensity of the effect of different nicotine salts (Table 1