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After various treatments of RBL, cell supernatants were collected and the LTC 4 content determined by an enzyme immunoassay kit from Cayman Chemicals (Ann Arbor, MI) according to the manufacturers protocol

On the other hand, Grapefruit juice can interfere with meloxicam metabolism and increase blood concentration, so healthcare providers recommend against its consumption while on treatment with meloxicam

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Results and Discussion Development of Chromatographic Method Isocratic separation for all abundant cation peaks (Li+, Na+, NH 4 +, K+, Mg+, and Ca+) was achieved with baseline resolution of the ammonium and other peaks at 20mM MSA concentration