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In addition, experiments where airway smooth muscle was pretreated with high concentrations of the purified aliphatic side chain of salmeterol failed to affect its long duration of salmeterol, which would have been expected to occur if anchored binding to an exosite was the primary mechanism responsible for its long duration of action (Bergendal A et al 1996)

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Gene regulation of filaggrin and other skin barrier proteins via aryl hydrocarbon receptor

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