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Notably, miR-122 can exert a protective function in APAP-induced hepatotoxicity by modulating CYP1A2 and CYP2E1 (Chowdhary et al., 2017)

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Posttranslational modification of histones involves covalent modification of specific sites and residues that form specific three-dimensional arrangements of nucleosomes that control the accessibility to transcriptional factors to genes to induce gene expression
