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Though not as detrimental as smoking a pack of cigarettes a day, smoking even one cigarette a day also should be avoided

abrupt withdrawal from alcohol or other sedatives

(Practical Use) 150 mg once daily 3 days Then 150 mg twice daily Start 12 weeks before the quit date Continue for 36 months Efficacy: ~64% higher odds of sustained abstinence at 6 months vs placebo Bupropion SR vs XL: Is Once-Daily Dosing Enough to Change Practice

no menthol restriction (group A) and (2) the greatest reductions in cigarettes per day where menthol is prohibited in cigarettes but where menthol e-cigarettes are available as a substitute (group B) compared with groups A and C